Welcome to the VUS Notifier

Variant of Uncertain (or unknown) Significance (VUS) Notifier is a powerful tool designed for research purposes, allowing you to stay updated on VUS classification changes. Explore any genetic variant in the HGVS format. Please note that this application is intended for research purposes only and should not be used as a decision-making tool in medical practice.

Proceed to register or login and start exploring genetic variants with ease. Stay informed about the latest research developments!

Features:

• Search Variants: Easily search for variants using the HGVS format, such as NM_007294.4:c.5509T>G.
• Save to Watchlist: Save variants to your watchlist and receive notifications about updates. Notifications are sent out regularly to ensure you stay informed.
• Variant information is pulled from multiple databases:
• ClinVar
• VEP (Variant Effect Predictor)
• LOVD (Leiden Open Variation Database)
• PubMed

If you enjoy using the application and would like to support its development, feel free to make a donation by clicking on the link.

This application was created by the Institute of molecular genetics and genetic engineering, University of Belgrade with the support of funding from the SAIGE project.